Fragrance mix II 14% pet. NA70 (CDI,CDIS,AC,ACS,NA,NAS,AU,EU,IC,BB,SID,PED/PF/CG,HD,LU)

CAS#: 91-64-5, 31906-04-5, 106-22-9, 4602-84-0, 5392-40-5, 101-86-0, 8002-74-2

Fragrance mix II contains the six additional substances that are often found in a variety of products: Coumarin, Lyral, Citronellol, Farnesol, Citral, a-Hexylcinnamicaldehyde. Fragrances can be found in most products. They are used to add flavor or scent to a product or may mask a product's unpleasant smell. They may come from natural (animals or plants) or synthetic sources.

How can you avoid contact with this allergen?

Avoid products that list any of the following names in the ingredients:

• 2H-1-Benzopyran-2-one
• Coumarin [NF X]
• Tonka bean camphor
• 1,2-Benzopyrone
• 2-Oxo-1,2-benzopyran
• 2-Propenoic acid, 3-(2-hydroxyphenyl)-, delta-lactone
• 2-Propenoic acid, 3-(2-hydroxyphenyl)-delta-lactone
• 2H-1-Benzopyran, 2-oxo-
• 2H-1-Benzopyran-2-one
• 2H-Benzo(b)pyran-2-one
• 3-(2-Hydroxyphenyl)-2-propenoic delta-lactone
• 5,6-Benzo-alpha-pyrone
• 5-17-10-00143 (Beilstein Handbook Reference)
• AI3-00753
• Alpha-hexylcinnamic aldehyde • BRN 0383644
• Benzo-alpha-pyrone
• CCRIS 181
• Caswell No. 259C
• Cinnamic acid, o-hydroxy-, delta-lactone
• Citral
• Coumarin
• Coumarinic anhydride
• Coumarinic lactone
• Cumarin
• EINECS 202-086-7
• EPA Pesticide Chemical Code 127301
• Farnesol
• Lyral
• Rattex
• Tonka bean camphor
• cis-o-Coumaric acid anhydride
• cis-o-Coumarinic acid lactone
• o-Coumaric acid lactone
• o-Hydroxycinnamic acid lactone
• o-Hydroxycinnamic lactone
• 4-(4-Hydroxy-4-methylpentyl)-3-cyclohexene-1-carboxaldehyde
• BRN 2046455
• EINECS 250-863-4
• 3-Cyclohexene-1-carboxaldehyde, 4-(4-hydroxy-4-methylpentyl)-
• 4-(4-Hydroxy-4-methylpentyl)cyclohex-3-enecarbaldehyde
• 3-Cyclohexene-1-carboxaldehyde, 4-(4-hydroxy-4-methylpentyl)-
• 2,6-Dimethyl-2-octen-8-ol
• 3,7-Dimethyl-6-octen-1-ol
• 4-01-00-02188 (Beilstein Handbook Reference)
• AI3-25080
• BRN 1721507
• CCRIS 7452
• Cephrol
• Citronellol (ex. Java citronella oil) (natural)
• Citronellol (natural)
• EINECS 203-375-0
• Elenol
• FEMA No. 2309
• NSC 8779
• Rhodinol
• Rodinol
• 2,6,10-Dodecatrien-1-ol, 3,7,11-trimethyl-
• 3,7,11-Trimethyl-2,6,10-dodecatrienol
• 3,7,11-Trimethyl-2,6,10-dodecatrien-1-ol
• Trimethyl dodecatrienol

Comments The Fragrance Mix II consists of the following fragrances: 5% alpha-Hexyl cinnamaldehyde (PF164=10% pet.), 1% Citral (ST160=2% pet.), 0.5% Citronellol (PF161=1% pet.), 2.5% Farnesol (PF163=5% pet.), 2.5% Coumarin (PF162=5% pet.) and 2.5% Lyral (ST161=5% pet.) / for further information see the single allergens.
The Fragrance Mix II is a screener for a general sensitization to fragrances.
The 6 allergens in the Fragrance Mix II belong to the 26 fragrances that have to be declared on cosmetics if their concentration exceeds a certain limit.
If a positive skin reaction with unclear case history is observed the clinical relevans should be varified through a ROAT (repeated open application test).
The patch test substance is produced with 10 % hard paraffin to ensure the homogenity.
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